TARGT First is one of the most focused and affordable pan-solid cancer gene panels available, encompassing 72 of the most commonly mutated cancer-associated genes with a high level of evidence for both targeted therapy and prognostication.
This test covers the well-known genomic biomarkers for which NCCN and FDA-approved therapy options are available to treat solid cancers. It has been developed to make cancer biomarker testing affordable and accessible for every cancer patient.
Additionally, First SoLiQ test employs a combined NGS approach using both solid and liquid biopsy, referred to as SoLiQ. This innovative method enables clinicians to gain insights from both sample types, thus mitigating the limitations associated with each. By integrating the information from solid tissue and circulating tumor DNA, First SoLiQ provides a comprehensive view of the disease's genomic landscape, aiding in identifying more accurate clinically relevant genomic alterations and guide precise biomarker driven treatment decisions
Panel
Targt First solid
Targt First Liquid
First SoliQ
Sample Requirements
FFPE/Fresh Tissue
Whole Blood (ctDNA)
FFPE/Fresh Tissue + Whole Blood (ctDNA)
SNVs/InDels& CNAs Coverage inTARGT First
ABL1
ALK
APC
AR
ATM
BARD1
BMPR1A
BRAF
BRCA1
BRCA2
BRIP1
CDK12
CDK4
CDK6
CDKN2A
CHEK1
CHEK2
CTNNB1
EGFR
EPCAM
ERBB2
ERBB3
EZH2
FANCL
FGFR1
FGFR2
FGFR3
GAPDH
IDH1
IDH2
JAK2
KIT
KRAS
MAP2K1
MAP2K2
MDM2
MET (exon 14 skipping)
MLH1
MLH3
MSH2
MSH6
MUTYH
NRAS
PALB2
PDGFRA
PDGFRB
PIK3CA
PMS1
PMS2
POLD1
POLE
POLH
PTEN
RAD50
RAD51
RAD51B
RAD51C
RAD51D
RAD54L
RB1
RET
ROS1
SMAD4
STK11
TP53
TSC1
TSC2
Gene FusionsCoverage inTARGT First
ALK
FGFR2
FGFR3
MET (exon 14 skipping)
NRG1
NRG2
NTRK1
NTRK2
NTRK3
RET
ROS1
Benefits of TARGT First Gene Panel Testing
Targeted Therapy Guidance
Identifying specific genomic alterations, such as mutations, amplifications, or fusions, helps identify potential therapeutic targets that assist oncologists in selecting the most appropriate targeted therapies for individual patients, increasing the likelihood of treatment success.
Prognostic Information
Certain genetic alterations can influence the prognosis of cancer patients, such as indicating a higher likelihood of disease recurrence or metastasis. This gene panel helps oncologists better understand the patient’s disease trajectory and tailor their management strategies by identifying these prognostic biomarkers.
Cost-Effectiveness
This gene panel is designed to make cancer biomarker testing affordable and accessible for all cancer patients. The test optimizes cost without compromising the essential genes for analysis. This affordability enables a broader population of patients to benefit from genomic profiling and personalized treatment approaches, ultimately improving patient outcomes.
Combined NGS Approach
This gene panel utilizes a combined NGS approach that includes solid and liquid biopsy samples. This approach enhances the resolution of the disease genomic landscape by leveraging the strengths of each sample source.
Why Choose 4baseCare's TARGT First Cancer Gene Panel?
Comprehensive Analysis
Our Cancer Gene Panel thoroughly assesses clinically relevant genes, ensuring accurate and reliable results.
Advanced Technology
We utilize cutting-edge next generation sequencing technology to deliver precise and detailed genetic information.
Expert Team
Our team of experienced genetic counselors and healthcare professionals will guide you through the testing process, answer your questions, and help you understand the implications of the results.
Confidentiality and Privacy
We adhere to strict privacy protocols and maintain the confidentiality of your genetic information.
Get Started Now by Requesting Your Test
Resources
TARGT First
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