Hereditary Cancer Test

Genomic variations/mutations/aberrations in the genes you are born with can increase your cancer risk. Our NGS (Next-Generation Sequencing) based Hereditary Cancer genetic panels analyze genes associated with cancer risk DDR (DNA Damage Repair), Mismatch Repair (MMR), and HRR (Homologous Recombination Repair) pathways. The panel includes genes associated with familial and hereditary cancers (Breast, Ovarian, Prostate, Pancreatic, Colon, etc).

As per ACMG guidelines, the detected variants are classified as pathogenic, likely pathogenic, VUS (Variant of Unknown Significance), likely benign, and benign. This may contribute to a high, moderate, or low cancer risk.

Some of the Germline variants, like in the BRCA gene, help identify cancer risk and help in making PARP (Poly-ADP-Ribose Polymerase) inhibitor targeted therapy treatment decisions.

Click on the below icon to know more about our Hereditary Cancer Test