Hereditary Cancer Gene Panel play a crucial role in identifying individuals who may carry inherited genetic mutations associated with various types of cancer. By detecting these mutations, clinicians can offer personalized care and develop tailored cancer management and treatment strategies.
4baseCare’s Hereditary Cancer Gene Panel utilize cutting-edge genomic sequencing technologies to analyze specific genes that are known to be associated with an increased risk of developing hereditary cancers. The panels include a comprehensive set of genes carefully selected based on their established links to specific cancer types. These genes may include well-known cancer susceptibility genes such as BRCA1 and BRCA2 and other genes associated with breast, ovarian, colorectal, prostate, and other germline-mutated cancers.
Hereditary Cancer Gene Panel Portfolio
Germline +
Germline+ test analyzes 163 genes (including BRCA 1/2) associated with different cancers: breast, ovary, uterus, prostate, gastrointestinal system, stomach, colon, rectum, small bowel & pancreas, amongst other cancers.
This test also screens the Homologous Recombination Repair pathway genes (HRR pathway genes) and Mismatch repair pathway genes (MMR genes) of clinical importance, which will help Oncologists make clinical decisions for targeted therapy, including PARP inhibitor therapy in specific cancer types
Key Benefits of Hereditary Cancer Gene Panel in Personalized Cancer Care
Early Detection and Preventive Care
By identifying inherited cancer-related mutations, hereditary gene panels allow for proactive health management. Individuals with detected mutations can adopt lifestyle changes, undergo more frequent screenings, and take preventive measures to reduce their cancer risk.
Risk Assessment for Family Members
Hereditary gene panel results offer valuable information for family members, who may also be at increased risk. Relatives can consider genetic testing and take preventive steps if they carry the same mutations.
Personalized Treatment Options
Knowing specific genetic mutations helps oncologists create tailored treatment strategies. For certain mutations, targeted therapies (such as PARP inhibitors for BRCA1/2 mutations) can be more effective, improving treatment outcomes.
Guidance on Surveillance and Follow-Up Care
Individuals who test positive for hereditary cancer mutations can benefit from tailored surveillance programs. Regular screenings and follow-up care plans are designed based on specific genetic risks, allowing for earlier detection and better management of potential cancers.
Get Started with Hereditary Cancer Gene Panel Testing
Consult with our Genetic Counsellor to learn more about hereditary cancer risks and testing options.